Database : HANSEN Search on : DOENCAS DOS ANIMAIS [Subject descriptor] References found : 3 [refine] Displaying: 1 .. 3   in format [Detailed]

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Id: 13318 Author: Hendler, Sheldon S; McCarty, Mark F Title: Thalidomide for autoimmune disease ..- Source: s.l; s.n; apr. 1983. 7 p. . Abstract: The therapeutic efficacy of thalidomide in erythema nodosum leprosum suggests that thalidomide might play a useful therapeutic role in other human immune-complex diseases. Thalidomide has shown anti-inflammatory or immunosuppressive actions in several animal models. Current evidence suggests that its rapid activity in ENL may result from suppression of neutrophil chemotaxis and phagocytosis. Scattered anecdotal clinical reports of apparent response to thalidomide in various autoimmune diseases are hardly conclusive, but underline the desirability of appropriate pilot trials of thalidomide in autoimmune diseases, particularly those in which immune complex deposition plays a prominent role. Provided that a contraindication in fertile women is strictly observed, thalidomide therapy appears to be quite safe.(AU). Descriptors: DOENCAS DOS ANIMAIS/quimioter DOENCAS AUTO-IMUNES/quimioter MODELOS ANIMAIS DE DOENCAS REJEICAO DE ENXERTO TALIDOMIDA/uso terap - INFLAMACAO/quimioter  INFLAMACAO/vet Limits: RELATO DE CASO HUMANO ANIMAL FEMININO COBAIAS RATOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01210

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Id: 13270 Author: Smith, Jerome H; Folse, Dean S; Long, Earl G; Christie, John D; Crouse, Dennis T; Tewes, Michael E; Gatson, Alice M; Lynn Ehrhardt, R; File, Sharon K; Kelly, Michael T Title: Leprosy in wild armadillos (Dasypus novemcinctus) of the Texas Gulf Coast: epidemiology and mycobacteriology ..- Source: s.l; s.n; aug. 1983. 4 p. mapas, tab. Abstract: A significant prevalence of leprosy has been demonstrated in wild Louisiana armadillos. The Texas Gulf Coast still has endemic human leprosy, and recent mores in Texas have markedly increased armadillo-human contact. Armadillos were screened by physical examination, and by ear-snip and slit-scrape technique. Animals that screened positive were sacrificed and necropsied under aseptic conditions. Liver, spleen, gross lesions, and four groups of lymph nodes were cultured for mycobacteria and were studied histologically. Base ratios and DNA homology with Mycobacterium leprae were determined on mycobacteria from two armadillos (and two tissues from one of these); these studies indicate that the organism found in Texas armadillos is M leprae. Twenty-one of the armadillos were leprous--4.66%. The local prevalence varied from 1.0% to 15.4%. Epidemiologic implications of these findings and the occurrence of other concomitant mycobacterial infections are discussed.(AU). Descriptors: DOENCAS DOS ANIMAIS/epidemiol TATUS/microbiol HANSENIASE/epidemiol HANSENIASE/patol HANSENIASE/vet LINFONODOS/microbiol TRIAGEM DE MASSA/vet MYCOBACTERIUM/isol MYCOBACTERIUM LEPRAE/isol XENARTROS/microbiol - TEXAS Limits: ANIMAL MASCULINO FEMININO SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 01640/s

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Id: 12324 Author: Smith, Jerome H; Folse, Dean S; Long, Earl G; Christie, John D; Crouse, Dennis T; Tewes, Michael E; Gatson, Alice M; Ehrhardt, R. Lynn; File, Sharon K; Kelly, Michael T Title: Leprosy in wild armadillos (Dasypus novemcinctus) of Texas Gulf Coast: epidemiology and mycobacteriology ..- Source: s.l; s.n; 1983. 14 p. tab, mapas. Descriptors: DOENÇAS DOS ANIMAIS TATUS HANSENIASE HANSENIASE HANSENIASE TRIAGEM DE MASSA MYCOBACTERIUM MYCOBACTERIUM LEPRAE TEXAS Linfonodos/MI Linfonodos/MI Limits: ANIMAL Location: BR191.1; 08718/s

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